Nov 23 2024
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Craniomaxillofacial Research Center

Regeneration of dental pulp complex in closed apex necrotic teeth using mesenchymal stem cell.

Summary of the necessity of project implementation


Reconstructive endodontics is one of the most remarkable advances in dentistry. The idea that damaged structures can be replaced and functions such as pain and immunocompetence can be achieved in previously necrotic and infected root canal systems has been a groundbreaking idea. Since the introduction of regenerative pulp therapy as a viable treatment in the early 2000s, endodontists and other scientists have continued to discover its significant benefits for immature teeth and its capacity to overcome the limitations of conventional root canal treatment. Teeth with incomplete root development have short roots with thin walls, which compromises their longevity. Through the reconstructive procedure, the root can continue to grow, which is a significant advantage over conventional root canal treatment and is especially valuable for young patients, as tooth preservation is critical for their skeletal and dental development. The endodontic restorative protocol provides clinicians with a relatively standardized procedure. The aim of this study is to evaluate a new treatment method for mature teeth that may provide long-term success, leading to a normal shift towards pulp tissue regeneration.


Moderator: Dr. Jafar A

Start year: 2021

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