.png){kind=small}
Identification of diagnostic and prognostic biomarkers in lung adenocarcinoma through integrated bioinformatics analysis and real time PCR validation
https://cmfrc.tums.ac.ir//news/Identification-of-diagnostic-and-prognostic-biomarkers-in-lung-adenocarcinoma-through-integrated-bioinformatics-analysis-and-real-time-PCR-validation/321232
Abstract Lung cancer is the third most common cancer in the US with a 5-year survival rate of 17%. Non-small cell lung cancer, especially adenocarcinoma, prevails. Therefore, early detection and biomarker discovery are extremely important. This study uses deep learning to find new biomarkers for lung adenocarcinoma. RNA-Seq data from 522 samples, including 506 lung adenocarcinoma patients and 16 healthy controls, were analyzed. DEGs were identified after strict preprocessing, and deep learning a
Investigating and Comparing the Effect of Portulaca oleracea, Vaccinium myrtillus, and Berberis vulgaris on Oral Squamous Cell Carcinoma in an Vitro Study
https://cmfrc.tums.ac.ir//article/Investigating-and-Comparing-the-Effect-of-Portulaca-oleracea,-Vaccinium-myrtillus,-and-Berberis-vulgaris-on-Oral-Squamous-Cell-Carcinoma-in-an-Vitro-Study
Abstract Background and Aim Oral squamous cell carcinoma (OSCC) is a growing health problem worldwide, for which standard treatment strategies have failed to increase its recovery rate significantly. In recent decades, many studies have investigated herbal or natural compounds for the prevention and treatment of OSCC. The present study was performed to investigate the effects of the extract of Portulaca oleracea seed, Berberis vulgaris, and Vaccinium myrtillus fruit on the OSCC. Experimental pro
Gene expression of one important microRNA in blood and tissue samples of oral squamous cell carcinoma
https://cmfrc.tums.ac.ir//Article/-Gene-expression-of-one-important-microRNA-in-blood-and-tissue-samples-of-oral-squamous-cell-carcinoma-
Abstract Introduction Oral Squamous Cell Carcinoma (OSCC) is one of the most common oral malignancies, which accounts for 80-90% of malignant neoplasms of the oral cavity. MicroRNAs (miRNAs) are small RNA molecules that regulate post-transcriptional gene expression by targeting mRNAs. Materials and Methods In this case-control study, 40 patients with oral squamous cell carcinoma and 40 healthy individuals as control were studied. Blood samples were collected from both groups. Also, 30 cancer tis
Human Epididymis Protein 4 Gene Expression as a Biomarker in Patients with Ovarian Cancer in Iran
https://cmfrc.tums.ac.ir//news/Human-Epididymis-Protein-4-Gene-Expression-as-a-Biomarker-in-Patients-with-Ovarian-Cancer-in-Iran
Abstract Introduction Ovarian cancer is one of the most common malignancies in women and the fifth cause of cancer-related deaths in women worldwide. Contrary to the challenges in developing new clinical markers using the conventional methods, recent advances in genomics and proteomics have led to identification of candidate and promising biomarkers for the diagnosis of ovarian cancer. Human epididymis protein 4 (HE4) is such a marker that has recently been reported to correlate with recurrence
Expression of Two Basic mRNA Biomarkers in Peripheral Blood of Patients with Non Small Cell Lung Cancer Detected by Real Time RT PCR, Individually and Simultaneously
https://cmfrc.tums.ac.ir//Article/Expression-of-Two-Basic-mRNA-Biomarkers-in-Peripheral-Blood-of-Patients-with-Non-Small-Cell-Lung-Cancer-Detected-by-Real-Time-RT-PCR,-Individually-and-Simultaneously
Abstract Introduction Although extensive research has been conducted on lung cancer markers, a singular clinically applicable marker has not been found yet. The objective of this study was to evaluate the sensitivity and the specificity of carcinoembryonic antigen (CEA) mRNA and lung-specific X protein (LUNX) mRNA biomarkers in peripheral blood to detect lung cancer individually and simultaneously. Methods Thirty patients affected by lung cancer and 30 healthy individuals were studied in this re
انتقادات و پیشنهادات خود را برای ما ارسال کنید