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کلیدواژه
https://cmfrc.tums.ac.ir//کلیدواژه/oral_squamous_cells_carcinoma
mRNA Biomarkers for Detection of Oral Squamous Cell Cancer https//cmfrc.tums.ac.ir//Article/-mRNA-Biomarkers-for-Detection-of-Oral-Squamous-Cell-Cancer- Abstract Objectives Cancer is one of the main causes of death in the world. Changes in the expression of CK19 and CEA genes in peripheral blood of OSCC patients were examined for early diagnosis. Methodology The participants were 36 patients and 36 normal individuals. CK19 and CEA of blood serum were measured through Real-Time PCR. The relations
مقالات علمی
https://cmfrc.tums.ac.ir//article/صفحه:12
لیست اخبار صفحه 12 Efficacy of adipose derived stem cells for regeneration of localized mandibular bone defects 1402/11/14 - Salivary antioxidant levels in pemphigus vulgaris patients compared to the healthy people 1402/11/14 - Real Time RT PCR Detection of HCN4 and ADAM8 Genes in Ventilator Associated Pneumonia Patients who Hospitalized in Intensive Care Unit 1402/11/14 - Histopathological Comparison between Bone Marrow and Periodontium derived Stem Cells for Bone Regeneration in Rabbit Calvari
Potential of IP 10 EGFR CK17 and ANXA1 as Non Invasive Biomarkers for the Diagnosis of Oral Squamous Cell Carcinoma
https://cmfrc.tums.ac.ir//Article/-Potential-of-IP-10-EGFR-CK17-and-ANXA1-as-Non-Invasive-Biomarkers-for-the-Diagnosis-of-Oral-Squamous-Cell-Carcinoma-
Abstract Introduction Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity. Early diagnosis and the identification of non-invasive biomarkers for disease monitoring are essential. This study aimed to evaluate the expression of genes involved in inflammation (IP-10), cellular proliferation (EGFR), epithelial differentiation (CK17), and cellular regulation (ANXA1) in the peripheral blood of OSCC patients compared with healthy individuals. Materials and Methods In th
Identification of diagnostic and prognostic biomarkers in lung adenocarcinoma through integrated bioinformatics analysis and real time PCR validation
https://cmfrc.tums.ac.ir//news/Identification-of-diagnostic-and-prognostic-biomarkers-in-lung-adenocarcinoma-through-integrated-bioinformatics-analysis-and-real-time-PCR-validation/321232
Abstract Lung cancer is the third most common cancer in the US with a 5-year survival rate of 17%. Non-small cell lung cancer, especially adenocarcinoma, prevails. Therefore, early detection and biomarker discovery are extremely important. This study uses deep learning to find new biomarkers for lung adenocarcinoma. RNA-Seq data from 522 samples, including 506 lung adenocarcinoma patients and 16 healthy controls, were analyzed. DEGs were identified after strict preprocessing, and deep learning a
Evaluation of miR 155 Expression in Peripheral Blood Samples of COPD Patients
https://cmfrc.tums.ac.ir//news/Evaluation-of-miR-155-Expression-in-Peripheral-Blood-Samples-of-COPD-Patients
Abstract Introduction Chronic obstructive pulmonary disease (COPD) is a progressive, irreversible chronic inflammatory disorder characterized by the increased recruitment of monocytes, lymphocytes, and neutrophils. Beyond the lungs, COPD is associated with systemic inflammation, skeletal complications such as osteoporosis, and poor oral and periodontal health, all of which are clinically relevant in oral and maxillofacial practice. This study aims to investigate the changes in miR-155 expression
Investigating the Level of MUC5B Expression in the Plasma of Patients with Idiopathic Pulmonary Fibrosis (IPF) Compared to Healthy Individuals
https://cmfrc.tums.ac.ir//article/Investigating-the-Level-of-MUC5B-Expression-in-the-Plasma-of-Patients-with-Idiopathic-Pulmonary-Fibrosis-(IPF)-Compared-to-Healthy-Individuals
Abstract Introduction Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease associated with high morbidity and mortality. Genetic factors, particularly the MUC5B promoter polymorphism, have been strongly implicated in disease pathogenesis. Given the shared embryological origin of the respiratory and oral epithelia, investigating systemic MUC5B expression may provide insights relevant to craniofacial and mucosal health. This study aimed to evaluate MUC5B gene expression i
Evaluation of NCBP2 Gene Expression in Patients with Oral Squamous Cell Carcinoma Compared to Healthy Individuals
https://cmfrc.tums.ac.ir//news/Evaluation-of-NCBP2-Gene-Expression-in-Patients-with-Oral-Squamous-Cell-Carcinoma-Compared-to-Healthy-Individuals
Abstract Introduction Oral squamous cell carcinoma (OSCC) is a widespread, aggressive disease with low survival rates due to late diagnosis and a lack of effective, noninvasive biomarkers. The nuclear cap-binding protein subunit 2 (NCBP2), involved in mRNA regulation, has been implicated in tumorigenesis. This study aimed to evaluate NCBP2 mRNA expression in plasma samples from patients with OSCC to assess its potential as a circulating diagnostic biomarker. Materials and Methods Fifteen patient
Comparing the Expression Levels of GCG and FBN 1 in the Plasma of Patients with Basal Cell Carcinoma (BCC) and Healthy Individuals
https://cmfrc.tums.ac.ir//news/Comparing-the-Expression-Levels-of-GCG-and-FBN-1-in-the-Plasma-of--Patients-with-Basal-Cell-Carcinoma-(BCC)-and-Healthy-Individuals
Abstract Introduction One of the most common types of skin cancer is basal cell carcinoma (BCC), which puts a big burden on the healthcare system. Direct and dermoscopic examinations are used to diagnose basal cell carcinoma. GCG is a protein-coding gene expressed in various cells throughout the body, including the small intestine, brain, and skin. Fibrillin-1 is an extracellular protein found in many body tissues. In this study, we compare the expression of GCG and FBN1 genes in the blood of pa
Real time PCR technique for diagnosing respiratory diseases miR155 miR17 miR 181 Expression and COPD
https://cmfrc.tums.ac.ir//Article/Real-time-PCR-technique-for-diagnosing-respiratory-diseases-miR155-miR17-miR-181-Expression-and-COPD
Abstract Background and Objective Chronic Obstructive Pulmonary Disease (COPD) is a progressive inflammatory condition with limited non-invasive biomarkers for diagnosis and monitoring. Circulating microRNAs (miRNAs), due to their involvement in inflammation, oxidative stress, and tissue remodeling, offer potential as molecular biomarkers. This study aimed to compare the expression of miR-155, miR-17, and miR-181 in COPD patients versus healthy individuals to assess their diagnostic value. Metho
Mir 148 and Mir 375 Expression in Oral Squamous Cell Carcinoma Patients with Oral Infection in Comparison with Oscc Patients without Oral Infection
https://cmfrc.tums.ac.ir//news/-Mir-148-and-Mir-375-Expression-in-Oral-Squamous-Cell-Carcinoma-Patients-with-Oral-Infection-in-Comparison-with-Oscc-Patients-without-Oral-Infection-
Abstract Introduction Oral squamous cell carcinoma is a multifactorial disease that is the sixth most common cancer worldwide. MicroRNAs have been confirmed to play a role in oral squamous cell carcinoma, acting as either oncogenes or tumor suppressor genes. This study examined the expression level and role of microR-148 and microR-375 in oral cancer.Materials and Methods In this study, we used 30 cancer samples with infection and 30 cancer samples without infection. To analyze the expression of
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