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کلیدواژه
https://cmfrc.tums.ac.ir//کلیدواژه/infection/صفحه:1
MCP1 IL6 TMPRSS2 and CRP Gene Expression in Peripheral Blood of COVID19 Patients with a History of COPD and Comparison with Healthy Individuals https//cmfrc.tums.ac.ir//article/MCP1-IL6--TMPRSS2-and-CRP-Gene-Expression-in-Peripheral-Blood-of-COVID19-Patients-with-a-History-of-COPD-and-Comparison-with-Healthy-Individuals Abstract Introduction Chronic obstructive pulmonary disease (COPD) is associated with persistent airway inflammation and an increased risk of adverse outcomes following coronavir
مقالات علمی
https://cmfrc.tums.ac.ir//article/صفحه:8
لیست اخبار صفحه 8 Three Markers in Cancerous and Healthy Cells of Patients with Non Small Cell Lung Carcinoma (NSCLC) 1402/12/05 - The effects of cross linked/uncross linked electrospun fibrinogen/polycaprolactone nanofibers on the proliferation of normal human epidermal keratinocytes 1402/12/05 - Differentiation of Periodontal Ligament Stem Cells Into Osteoblasts on Hybrid Alginate/ Polyvinyl Alcohol/ Hydroxyapatite Nanofibrous Scaffolds 1402/12/05 - Activation Toll Like Receptor7 (TLR7) Respon
Potential of IP 10 EGFR CK17 and ANXA1 as Non Invasive Biomarkers for the Diagnosis of Oral Squamous Cell Carcinoma
https://cmfrc.tums.ac.ir//Article/-Potential-of-IP-10-EGFR-CK17-and-ANXA1-as-Non-Invasive-Biomarkers-for-the-Diagnosis-of-Oral-Squamous-Cell-Carcinoma-
Abstract Introduction Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity. Early diagnosis and the identification of non-invasive biomarkers for disease monitoring are essential. This study aimed to evaluate the expression of genes involved in inflammation (IP-10), cellular proliferation (EGFR), epithelial differentiation (CK17), and cellular regulation (ANXA1) in the peripheral blood of OSCC patients compared with healthy individuals. Materials and Methods In th
Identification of diagnostic and prognostic biomarkers in lung adenocarcinoma through integrated bioinformatics analysis and real time PCR validation
https://cmfrc.tums.ac.ir//news/Identification-of-diagnostic-and-prognostic-biomarkers-in-lung-adenocarcinoma-through-integrated-bioinformatics-analysis-and-real-time-PCR-validation/321232
Abstract Lung cancer is the third most common cancer in the US with a 5-year survival rate of 17%. Non-small cell lung cancer, especially adenocarcinoma, prevails. Therefore, early detection and biomarker discovery are extremely important. This study uses deep learning to find new biomarkers for lung adenocarcinoma. RNA-Seq data from 522 samples, including 506 lung adenocarcinoma patients and 16 healthy controls, were analyzed. DEGs were identified after strict preprocessing, and deep learning a
Evaluation of NCBP2 Gene Expression in Patients with Oral Squamous Cell Carcinoma Compared to Healthy Individuals
https://cmfrc.tums.ac.ir//news/Evaluation-of-NCBP2-Gene-Expression-in-Patients-with-Oral-Squamous-Cell-Carcinoma-Compared-to-Healthy-Individuals
Abstract Introduction Oral squamous cell carcinoma (OSCC) is a widespread, aggressive disease with low survival rates due to late diagnosis and a lack of effective, noninvasive biomarkers. The nuclear cap-binding protein subunit 2 (NCBP2), involved in mRNA regulation, has been implicated in tumorigenesis. This study aimed to evaluate NCBP2 mRNA expression in plasma samples from patients with OSCC to assess its potential as a circulating diagnostic biomarker. Materials and Methods Fifteen patient
Real time PCR technique for diagnosing respiratory diseases miR155 miR17 miR 181 Expression and COPD
https://cmfrc.tums.ac.ir//Article/Real-time-PCR-technique-for-diagnosing-respiratory-diseases-miR155-miR17-miR-181-Expression-and-COPD
Abstract Background and Objective Chronic Obstructive Pulmonary Disease (COPD) is a progressive inflammatory condition with limited non-invasive biomarkers for diagnosis and monitoring. Circulating microRNAs (miRNAs), due to their involvement in inflammation, oxidative stress, and tissue remodeling, offer potential as molecular biomarkers. This study aimed to compare the expression of miR-155, miR-17, and miR-181 in COPD patients versus healthy individuals to assess their diagnostic value. Metho
Mir 148 and Mir 375 Expression in Oral Squamous Cell Carcinoma Patients with Oral Infection in Comparison with Oscc Patients without Oral Infection
https://cmfrc.tums.ac.ir//news/-Mir-148-and-Mir-375-Expression-in-Oral-Squamous-Cell-Carcinoma-Patients-with-Oral-Infection-in-Comparison-with-Oscc-Patients-without-Oral-Infection-
Abstract Introduction Oral squamous cell carcinoma is a multifactorial disease that is the sixth most common cancer worldwide. MicroRNAs have been confirmed to play a role in oral squamous cell carcinoma, acting as either oncogenes or tumor suppressor genes. This study examined the expression level and role of microR-148 and microR-375 in oral cancer.Materials and Methods In this study, we used 30 cancer samples with infection and 30 cancer samples without infection. To analyze the expression of
Biomarkers for Oral Squamous Cell Carcinoma (miR 24, miR 200, and miR 34): Screening and Detection MicroRNA
https://cmfrc.tums.ac.ir//news/Biomarkers-for-Oral-Squamous-Cell-Carcinoma-(miR-24,-miR-200,-and-miR-34):-Screening-and-Detection-MicroRNA
Abstract Introduction Oral squamous cell carcinoma (OSCC) includes about 90% of all oral malignant tumors, and most of them are diagnosed in advanced stages. This study investigated the expression changes of miR-24, miR-200, and miR-34 in saliva samples of patients with oral squamous cell carcinoma, for early diagnosis. Methods In this study, 30 patients and 30 healthy individuals were selected. After RNA extraction and cDNA synthesis, the expression levels of miR-24, miR-200, and miR-34 in sali
Expression Profile and Relationships between microRNAs as Biomarkers in COPD Patients
https://cmfrc.tums.ac.ir//news/Expression-Profile-and-Relationships-between-microRNAs-as-Biomarkers-in-COPD-Patients
Abstract Chronic obstructive pulmonary disease is a chronic inflammatory lung disease that causes airflow obstruction in the lungs. In fact, it is a lung disease that can cause involvement of respiratory tracts, lung tissue or blood vessels. There is still no accurate diagnostic tool for COPD. Among various biomarkers, the current review focuses on different types of miRNAs in COPD which have been studied. Many target cells and molecules, microRNAs are involved in the pathogenesis of COPD. Micro
Evaluation of Chemokines and Cytokines as Biomarkers for Disease Severity in COVID 19 Infected Patients
https://cmfrc.tums.ac.ir//Article/Evaluation-of-Chemokines-and-Cytokines-as-Biomarkers-for-Disease-Severity-in-COVID-19-Infected-Patients
Abstract Background Alterations in cytokine and chemokine levels during SARS-CoV-2 infection may serve as indicators of disease severity. Objectives This study aimed to evaluate the levels of plasma cytokines and chemokines in patients with COVID-19. Methods The study included 120 COVID-19 patients, divided into severe, mild, and recovered categories (n = 40 for each group). Plasma levels of cytokines such as interleukin 8 (IL-8) and tumor necrosis factor α (TNF-α) were measured usin
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