مرکز تحقیقات جراحی های فک و صورت

کلیدواژه

https://cmfrc.tums.ac.ir//کلیدواژه/infection/صفحه:1

MCP1 IL6 TMPRSS2 and CRP Gene Expression in Peripheral Blood of COVID19 Patients with a History of COPD and Comparison with Healthy Individuals https//cmfrc.tums.ac.ir//article/MCP1-IL6--TMPRSS2-and-CRP-Gene-Expression-in-Peripheral-Blood-of-COVID19-Patients-with-a-History-of-COPD-and-Comparison-with-Healthy-Individuals Abstract Introduction Chronic obstructive pulmonary disease (COPD) is associated with persistent airway inflammation and an increased risk of adverse outcomes following coronavir

مقالات علمی

https://cmfrc.tums.ac.ir//article/صفحه:8

لیست اخبار صفحه 8 Three Markers in Cancerous and Healthy Cells of Patients with Non Small Cell Lung Carcinoma (NSCLC) 1402/12/05 - The effects of cross linked/uncross linked electrospun fibrinogen/polycaprolactone nanofibers on the proliferation of normal human epidermal keratinocytes 1402/12/05 - Differentiation of Periodontal Ligament Stem Cells Into Osteoblasts on Hybrid Alginate/ Polyvinyl Alcohol/ Hydroxyapatite Nanofibrous Scaffolds 1402/12/05 - Activation Toll Like Receptor7 (TLR7) Respon

اخبار1

https://cmfrc.tums.ac.ir//news/صفحه:17

لیست اخبار صفحه 17 Two Molecular Markers of Early Non Small Cell Lung Carcinoma Based on Gene Expression in Peripheral Blood 1402/11/25 - Efficacy of low level laser for prevention of pain and trismus after impacted mandibular third molar surgery 1402/11/25 - Investigating gene expression level of MUC1 and CEA in pleural fluid of NSCLC lung cancer patients with real time RT PCR method 1402/11/25 - Multi Gene Expression in Anthracosis of the Lungs as One of the Risk Factors for Non Small Cell Lun

Potential of IP 10 EGFR CK17 and ANXA1 as Non Invasive Biomarkers for the Diagnosis of Oral Squamous Cell Carcinoma

https://cmfrc.tums.ac.ir//Article/-Potential-of-IP-10-EGFR-CK17-and-ANXA1-as-Non-Invasive-Biomarkers-for-the-Diagnosis-of-Oral-Squamous-Cell-Carcinoma-

Abstract Introduction Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity. Early diagnosis and the identification of non-invasive biomarkers for disease monitoring are essential. This study aimed to evaluate the expression of genes involved in inflammation (IP-10), cellular proliferation (EGFR), epithelial differentiation (CK17), and cellular regulation (ANXA1) in the peripheral blood of OSCC patients compared with healthy individuals. Materials and Methods In th

Identification of diagnostic and prognostic biomarkers in lung adenocarcinoma through integrated bioinformatics analysis and real time PCR validation

https://cmfrc.tums.ac.ir//news/Identification-of-diagnostic-and-prognostic-biomarkers-in-lung-adenocarcinoma-through-integrated-bioinformatics-analysis-and-real-time-PCR-validation/321232

Abstract Lung cancer is the third most common cancer in the US with a 5-year survival rate of 17%. Non-small cell lung cancer, especially adenocarcinoma, prevails. Therefore, early detection and biomarker discovery are extremely important. This study uses deep learning to find new biomarkers for lung adenocarcinoma. RNA-Seq data from 522 samples, including 506 lung adenocarcinoma patients and 16 healthy controls, were analyzed. DEGs were identified after strict preprocessing, and deep learning a

Comparison of the Expression of Cytokeratin 6 and 16 in Oral Lichen Planus Oral Lichenoid Lesions with Dysplasia and Oral Squamous Cell Carcinoma

https://cmfrc.tums.ac.ir//Article/Comparison-of-the-Expression-of-Cytokeratin-6-and-16-in-Oral-Lichen-Planus-Oral-Lichenoid-Lesions-with-Dysplasia-and-Oral-Squamous-Cell-Carcinoma

Abstract Introduction Oral lichen planus (OLP) and oral lichenoid lesions (OLL/OLR) are chronic inflammatory disorders of the oral mucosa with potential malignant transformation. Cytokeratins 6 and 16 (CK6, CK16) are markers of epithelial proliferation and have previously been reported to be elevated in inflammation, wound healing, and epithelial tumors. This study aimed to compare CK6 and CK16 mRNA expression across reticular OLP (ROLP), erosive OLP (EOLP), oral lichenoid lesions with dysplasia

Evaluation of NCBP2 Gene Expression in Patients with Oral Squamous Cell Carcinoma Compared to Healthy Individuals

https://cmfrc.tums.ac.ir//news/Evaluation-of-NCBP2-Gene-Expression-in-Patients-with-Oral-Squamous-Cell-Carcinoma-Compared-to-Healthy-Individuals

Abstract Introduction Oral squamous cell carcinoma (OSCC) is a widespread, aggressive disease with low survival rates due to late diagnosis and a lack of effective, noninvasive biomarkers. The nuclear cap-binding protein subunit 2 (NCBP2), involved in mRNA regulation, has been implicated in tumorigenesis. This study aimed to evaluate NCBP2 mRNA expression in plasma samples from patients with OSCC to assess its potential as a circulating diagnostic biomarker. Materials and Methods Fifteen patient

Comparing the Expression Levels of GCG and FBN 1 in the Plasma of Patients with Basal Cell Carcinoma (BCC) and Healthy Individuals

https://cmfrc.tums.ac.ir//news/Comparing-the-Expression-Levels-of-GCG-and-FBN-1-in-the-Plasma-of--Patients-with-Basal-Cell-Carcinoma-(BCC)-and-Healthy-Individuals

Abstract Introduction One of the most common types of skin cancer is basal cell carcinoma (BCC), which puts a big burden on the healthcare system. Direct and dermoscopic examinations are used to diagnose basal cell carcinoma. GCG is a protein-coding gene expressed in various cells throughout the body, including the small intestine, brain, and skin. Fibrillin-1 is an extracellular protein found in many body tissues. In this study, we compare the expression of GCG and FBN1 genes in the blood of pa

The Role of Oral Microbiota in the Development of Oral Squamous Cell Carcinoma Using MicroRNA and Apoptosis Related Gene Expression: An Exploratory Study

https://cmfrc.tums.ac.ir//article/The-Role-of-Oral-Microbiota-in-the-Development-of-Oral-Squamous-Cell-Carcinoma-Using-MicroRNA-and-Apoptosis-Related-Gene-Expression:-An-Exploratory-Study

Abstract Background and Objective Oral cancer is one of the malignant tumors of the head and neck region, which is associated with high mortality rates and has various negative effects on the aesthetics of patients. Therefore, access to high-quality care for early detection and appropriate surgical and drug treatments is crucial. To this end, researchers are investigating the mechanisms of carcinogenesis in cells and identifying the factors that affect it. The aim of this study was to investigat

مقایسه اثر انتی آنژیوژنیک تیابندازول نسبت به اواستین بر روی مدل ارگانویید کارسینوم سلول سنگفرشی دهان

https://cmfrc.tums.ac.ir//news/-مقایسه-اثر-انتی-آنژیوژنیک-تیابندازول-نسبت-به-اواستین-بر-روی-مدل-ارگانویید-کارسینوم-سلول-سنگفرشی-دهان

خلاصه ضرورت اجرای طرح کارسینوم سلول سنگفرشی دهانی (OSCC) یکی از شایع‌ترین انواع سرطان‌های دهانی است که با نرخ بالای مرگ‌ومیر همراه است. درمان‌های موجود همچون سیس‌پلاتین، علیرغم اثربخشی، دارای عوارض جانبی زیادی هستند و نیاز به درمان‌های جدید با اثرات جانبی کمتر احساس می‌شود. تیابندازول به‌عنوان یک ترکیب دارویی با پتانسیل اثرگذاری بر رشد سلول‌های سرطانی، می‌تواند گزینه‌ای امیدوارکننده برای درمان این نوع سرطان باشد. بررسی اثرات این دارو بر مورف

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