MCP1 IL6 TMPRSS2 and CRP Gene Expression in Peripheral Blood of COVID19 Patients with a History of COPD and Comparison with Healthy Individuals
https://cmfrc.tums.ac.ir//article/MCP1-IL6--TMPRSS2-and-CRP-Gene-Expression-in-Peripheral-Blood-of-COVID19-Patients-with-a-History-of-COPD-and-Comparison-with-Healthy-Individuals
Abstract Introduction Chronic obstructive pulmonary disease (COPD) is associated with persistent airway inflammation and an increased risk of adverse outcomes following coronavirus disease 2019 (COVID-19). While the lower airways have been the primary focus of most studies, the upper respiratory tract plays a critical role in SARS-CoV-2 entry and early symptom development. Inflammatory mediators, including interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and C-reactive protein (
A Comprehensive Study of the Global COVID 19 Pandemic and Fungal Co Infections: A Review
https://cmfrc.tums.ac.ir//article/-A-Comprehensive-Study-of-the-Global-COVID-19-Pandemic-and-Fungal-Co-Infections:-A-Review-
Abstract Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-19), which has resulted in high death tolls around the world and a significant health burden. The purpose of this study is to bring attention to the early diagnosis and treatment of fungal diseases in coronavirus disease 2019 (COVID-19) patients. Materials and Methods We searched peer-reviewed articles, reviews, surveillance reports, and clinical studies published from January 2020 to December 2023 using databases in
Comparative Study of Angiotensin Convertase Enzyme (ACE2) Gene Expression in Patients with Covid 19 By Molecular Method
https://cmfrc.tums.ac.ir//article/Comparative-Study-of-Angiotensin-Convertase-Enzyme-(ACE2)-Gene--Expression-in-Patients-with-Covid-19-By-Molecular-Method
Abstract Introduction The Covid 19 illness is triggered by a coronavirus known as SARS CoV-2. This particular virus spreads rapidly likely because of the Spike proteins affinity, to the human ACE2 cell receptor causing harm to organs, like the lungs in type 2 pneumocytes that abundantly express this receptor. Materials and Methods The research methodology used in this study involved a case control approach. Patients were referred by a specialist following diagnosis. A total of 50 samples, from i
Evaluation of Chemokines and Cytokines as Biomarkers for Disease Severity in COVID 19 Infected Patients
https://cmfrc.tums.ac.ir//Article/Evaluation-of-Chemokines-and-Cytokines-as-Biomarkers-for-Disease-Severity-in-COVID-19-Infected-Patients
Abstract Background Alterations in cytokine and chemokine levels during SARS-CoV-2 infection may serve as indicators of disease severity. Objectives This study aimed to evaluate the levels of plasma cytokines and chemokines in patients with COVID-19. Methods The study included 120 COVID-19 patients, divided into severe, mild, and recovered categories (n = 40 for each group). Plasma levels of cytokines such as interleukin 8 (IL-8) and tumor necrosis factor α (TNF-α) were measured usin
Prevalence of olfactory dysfunction in COVID 19 patients
https://cmfrc.tums.ac.ir//Article/-Prevalence-of-olfactory-dysfunction-in-COVID-19-patients-
Abstract Background Nowadays COVID-19 has become a pandemic in which global society experience multiple difficulties in management. It seems that olfactory dysfunction is one of the early occurring symptoms of this viral infection and many patients just show this symptom after they got infected. Considering so, olfactory dysfunction especially a decline in olfaction could potentially be used for screening purposes and preventing the disease to spread. Methods 50 PCR-verified SARS-CoV-2 infected
Clinical Significance and Different Expression of Dipeptidyl Peptidase IV and Procalcitonin in Mild and Severe COVID 19
https://cmfrc.tums.ac.ir//Article/-Clinical-Significance-and-Different-Expression-of-Dipeptidyl-Peptidase-IV-and-Procalcitonin-in-Mild-and-Severe-COVID-19
Abstract Background Coronavirus has become a global concern in 2019-20. The virus belongs to the coronavirus family, which has been able to infect many patients and victims around the world. The virus originated in the Chinese city of Wuhan, which eventually spread around the world and became a pandemic. Materials and Methods A total of 60 Patients with severe (n=30) and mild (n=30) symptoms of COIVD-19 were included in this study. Peripheral blood samples were collected from the patients. Real-
Quality of Life in Adolescents and Young Adults with Cleft Lip and Palate with and Without Speech Therapy During COVID 19
https://cmfrc.tums.ac.ir//Article/Quality-of-Life-in-Adolescents-and-Young-Adults-with-Cleft-Lip-and-Palate-with-and-Without-Speech-Therapy-During-COVID-19
Abstract Interventions ST group received at least 10 ST sessions, and group without ST didn’t receive ST during COVID-19. Main Outcome Measure (s) A virtual link of demographic and QOL adolescent cleft (QoLAdoCleft) questionnaires were sent to fill out. Results were extracted and transferred to SPSS. Results Total and subscales’ scores of QoLAdoCleft were lower in ST group than without ST but differences between them weren’t statistically significant (P > .05).
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