Mir 148 and Mir 375 Expression in Oral Squamous Cell Carcinoma Patients with Oral Infection in Comparison with Oscc Patients without Oral Infection

https://cmfrc.tums.ac.ir//news/-Mir-148-and-Mir-375-Expression-in-Oral-Squamous-Cell-Carcinoma-Patients-with-Oral-Infection-in-Comparison-with-Oscc-Patients-without-Oral-Infection-

Abstract Introduction Oral squamous cell carcinoma is a multifactorial disease that is the sixth most common cancer worldwide. MicroRNAs have been confirmed to play a role in oral squamous cell carcinoma, acting as either oncogenes or tumor suppressor genes. This study examined the expression level and role of microR-148 and microR-375 in oral cancer.Materials and Methods In this study, we used 30 cancer samples with infection and 30 cancer samples without infection. To analyze the expression of