بررسی بیان ژن های CK19وVEGFدر خون محیطی بیماران مبتلا به کارسینومای سلول های سنگ فرشی دهان (OSCC)

https://cmfrc.tums.ac.ir//news/بررسی-بیان-ژن-های-CK19وVEGFدر-خون-محیطی-بیماران-مبتلا-به-کارسینومای-سلول-های-سنگ-فرشی-دهان-(OSCC)

Abstract Background Oral squamous cell carcinoma (OSCC) is one of the 10 most common malignant tumors. This study aimed to evaluate the relevance of vascular endothelial growth factor (VEGF) and cytokeratin 19 (CK19) genes as biomarkers for diagnosis of OSCC.Methods In this study, 30 patients and 30 healthy individuals were selected. CK19 and VEGF were measured in peripheral blood using real-time polymerase chain reaction (PCR) technique. T-test was performed to analyze the data.Findings In pati