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مقالات علمی
https://cmfrc.tums.ac.ir//article/صفحه:8
لیست اخبار صفحه 8 Three Markers in Cancerous and Healthy Cells of Patients with Non Small Cell Lung Carcinoma (NSCLC) 1402/12/05 - The effects of cross linked/uncross linked electrospun fibrinogen/polycaprolactone nanofibers on the proliferation of normal human epidermal keratinocytes 1402/12/05 - Differentiation of Periodontal Ligament Stem Cells Into Osteoblasts on Hybrid Alginate/ Polyvinyl Alcohol/ Hydroxyapatite Nanofibrous Scaffolds 1402/12/05 - Activation Toll Like Receptor7 (TLR7) Respon
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https://cmfrc.tums.ac.ir//news/صفحه:17
لیست اخبار صفحه 17 Two Molecular Markers of Early Non Small Cell Lung Carcinoma Based on Gene Expression in Peripheral Blood 1402/11/25 - Efficacy of low level laser for prevention of pain and trismus after impacted mandibular third molar surgery 1402/11/25 - Investigating gene expression level of MUC1 and CEA in pleural fluid of NSCLC lung cancer patients with real time RT PCR method 1402/11/25 - Multi Gene Expression in Anthracosis of the Lungs as One of the Risk Factors for Non Small Cell Lun
MCP1 IL6 TMPRSS2 and CRP Gene Expression in Peripheral Blood of COVID19 Patients with a History of COPD and Comparison with Healthy Individuals
https://cmfrc.tums.ac.ir//article/MCP1-IL6--TMPRSS2-and-CRP-Gene-Expression-in-Peripheral-Blood-of-COVID19-Patients-with-a-History-of-COPD-and-Comparison-with-Healthy-Individuals
Abstract Introduction Chronic obstructive pulmonary disease (COPD) is associated with persistent airway inflammation and an increased risk of adverse outcomes following coronavirus disease 2019 (COVID-19). While the lower airways have been the primary focus of most studies, the upper respiratory tract plays a critical role in SARS-CoV-2 entry and early symptom development. Inflammatory mediators, including interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and C-reactive protein (
Comparison of the Expression of Cytokeratin 6 and 16 in Oral Lichen Planus Oral Lichenoid Lesions with Dysplasia and Oral Squamous Cell Carcinoma
https://cmfrc.tums.ac.ir//Article/Comparison-of-the-Expression-of-Cytokeratin-6-and-16-in-Oral-Lichen-Planus-Oral-Lichenoid-Lesions-with-Dysplasia-and-Oral-Squamous-Cell-Carcinoma
Abstract Introduction Oral lichen planus (OLP) and oral lichenoid lesions (OLL/OLR) are chronic inflammatory disorders of the oral mucosa with potential malignant transformation. Cytokeratins 6 and 16 (CK6, CK16) are markers of epithelial proliferation and have previously been reported to be elevated in inflammation, wound healing, and epithelial tumors. This study aimed to compare CK6 and CK16 mRNA expression across reticular OLP (ROLP), erosive OLP (EOLP), oral lichenoid lesions with dysplasia
Exosomal mRNAs/microRNAs in Osteogenesis and Bone Regeneration: From Signaling to Therapeutic Roles
https://cmfrc.tums.ac.ir//Article/Exosomal-mRNAs⁄microRNAs-in-Osteogenesis-and-Bone-Regeneration:-From-Signaling-to-Therapeutic-Roles
Abstract Bone regeneration remains a significant clinical challenge in conditions such as trauma, osteoporosis, and aging-related bone loss. Recent advances have highlighted the crucial role of extracellular vesicles, especially exosomes, in intercellular signaling pathways that support bone homeostasis and repair. Among their bioactive cargoes, exosomal RNAs—particularly messenger RNAs and microRNAs—have emerged as central regulators of osteogenesis by modulating gene expression, ce
Investigating the Level of MUC5B Expression in the Plasma of Patients with Idiopathic Pulmonary Fibrosis (IPF) Compared to Healthy Individuals
https://cmfrc.tums.ac.ir//article/Investigating-the-Level-of-MUC5B-Expression-in-the-Plasma-of-Patients-with-Idiopathic-Pulmonary-Fibrosis-(IPF)-Compared-to-Healthy-Individuals
Abstract Introduction Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease associated with high morbidity and mortality. Genetic factors, particularly the MUC5B promoter polymorphism, have been strongly implicated in disease pathogenesis. Given the shared embryological origin of the respiratory and oral epithelia, investigating systemic MUC5B expression may provide insights relevant to craniofacial and mucosal health. This study aimed to evaluate MUC5B gene expression i
Evaluation of NCBP2 Gene Expression in Patients with Oral Squamous Cell Carcinoma Compared to Healthy Individuals
https://cmfrc.tums.ac.ir//news/Evaluation-of-NCBP2-Gene-Expression-in-Patients-with-Oral-Squamous-Cell-Carcinoma-Compared-to-Healthy-Individuals
Abstract Introduction Oral squamous cell carcinoma (OSCC) is a widespread, aggressive disease with low survival rates due to late diagnosis and a lack of effective, noninvasive biomarkers. The nuclear cap-binding protein subunit 2 (NCBP2), involved in mRNA regulation, has been implicated in tumorigenesis. This study aimed to evaluate NCBP2 mRNA expression in plasma samples from patients with OSCC to assess its potential as a circulating diagnostic biomarker. Materials and Methods Fifteen patient
Tissue Engineering Using Differentiation of Endometrial Stem Cells into Ameloblast Cells and Implantation on Hydroxyapatite and Collagen Nanocomposite Scaffold
https://cmfrc.tums.ac.ir//news/Tissue-Engineering-Using-Differentiation-of-Endometrial-Stem-Cells-into-Ameloblast-Cells-and-Implantation-on-Hydroxyapatite-and-Collagen-Nanocomposite-Scaffold
Background Dental tissue engineering (DTE) is an inspiring biological approach to replacing lost teeth. The strength of the differentiation of basic endometrial cells to ameloblasts is yet to be fully understood. Moreover, the construction of a scaffold, upon which ameloblasts can both grow and replicate, has been a challenge in DTE. Methods This is an experimental study. Basic endometrial cells were first isolated and cultured before induction of differentiation to ameloblast cells by adjacency
Neural Differentiation of Wisdom Tooth Follicle Stem Cells on a Nano Hydrogel Scaffold Containing Salvia Chloroleucat to Treat Nerve injury in the Cancer of Nervous System
https://cmfrc.tums.ac.ir//news/Neural-Differentiation-of-Wisdom-Tooth-Follicle-Stem-Cells-on-a-Nano-Hydrogel-Scaffold-Containing-Salvia-Chloroleucat-to-Treat-Nerve-injury-in-the-Cancer-of-Nervous-System
Abstract The human third molar’s follicle is one of the sources of stem cells with high differentiation capacities which can be used in nervous system cancer treatment particularly in nerve damge. The purpose of this research was to identify the effects of the aqueous extract of Salvia chloroleuca on the differentiation of the human dental follicle-derived mesenchymal stem cells to neural cells for treti. In this experimental study, the method of culture of digested tissue fragments was us
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In vitro Effect of 810 nm and 940 nm Diode Laser Irradiation on Proliferation of Human Gingival Fibroblasts and Expression of Procollagen Gene
https://cmfrc.tums.ac.ir//news/In-vitro-Effect-of-810-nm-and-940-nm-Diode-Laser-Irradiation-on-Proliferation-of-Human-Gingival-Fibroblasts-and-Expression-of-Procollagen-Gene
ABSTRACT Factors promoting fibroblast proliferation and collagen synthesis can subsequently enhance wound healing. This study aimed to assess the effect of 810 and 940 nm diode laser on fibroblast proliferation and procollagen gene expression. In this study, human gingival fibroblasts were cultured in Dulbecco’s modified Eagle’s medium and underwent 810 and 940 nm diode laser irradiation once, twice, thrice and four times at 1, 3, 5 and 7 days after culture. The
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